一、 近五年论著（其中51篇为通讯或共同通讯）：

1.   Zheng RC#, Wang QD#, Lv SZ, Li CP, Wang CY, Chen WB, Wang H*. Automatic Liver Tumor Segmentation on Dynamic Contrast Enhanced MRI Using 4D Information: Deep Learning Model Based on 3D Convolution and Convolutional LSTM. IEEE Trans Med Imaging. 2022; doi: 10.1109/TMI.2022.3175461. 

2.   Zhang BY#, Huo YJ#, Yang ZD, Lv HH, Wang YL, Feng JF, Han Y*, Wang H*. Day to day blood pressure variability associated with cerebral arterial dilation and white matter hyperintensity. Hypertension. 2022; doi: 10.1161/HYPERTENSIONAHA.122.19269. 

3.   Su GH#, Xiao Y#, You C#, Zheng RC#, Zhao S#, Sun SY, Zhou JY, Lin LY, Wang H*, Shao ZM*, Gu YJ*, Jiang YZ*. Radiogenomic-based multiomic analysis reveals imaging intratumor heterogeneity phenotypes and therapeutic targets. Sci Adv. 2023 Oct 6;9(40):eadf0837. doi: 10.1126/sciadv.adf0837. 

4.   Wang J#, Li H#, Jia J, Shao X, Li Y, Zhou Y, Wang H*, Jin L*. Progressive Cerebrovascular Reactivity Reduction Occurs in Parkinson's Disease: A Longitudinal Study. Mov Disord. 2024 Jan;39(1):94-104. doi: 10.1002/mds.29671.

5.     Guo C#, Wang B#, Huo Y, Shan L, Qiao T, Yang Z, Liu M, Wang Y, Liu G, Liu Y*, Wang H*, Han Y*. The effects of P2 segment of posterior cerebral artery to thalamus blood supply pattern on gait in cerebral small vessel disease: A 7 T MRI based study. Neurobiol Dis. 2024 Jan;190:106372. doi: 10.1016/j.nbd.2023.106372.

6.   Wei L#, Du X#, Yang Z, Ding M, Yang B, Wang J, Long S, Qiao Z, Jiang Y, Wang Y*, Wang H*. Disrupted Topological Organization of White Matter Network in Angelman Syndrome. J Magn Reson Imaging. 2023 Apr;57(4):1212-1221.

7.   Yang X#, Liu Y#, Fu CX, Chu YH, Chen Q, Wang H*, Wei DX*, Yao YF*. Selectively Probing the Magnetic Resonance Signals of γ-Aminobutyric Acid in Human Brains In Vivo. J Magn Reson Imaging. 2023 Jun 13. doi: 10.1002/jmri.28853.

8.   Shi Z#, Zhao XY#, Zhu S, Miao XY, Zhang YF, Han SH, Wang B, Zhang BY, Ye XD, Dai YM, Chen CZ, Rao SX, Lin J, Zeng MS*, Wang H. Time-of-Flight intracranial MRA on 3T vs. 5T vs. 7T: visualization of distal small cerebral arteries. Radiology, 2022; doi: 10.1148/radiol.220114. (senior author) 

9.   Wang C#, Huang Y#, Liu C, Liu F, Hu X, Kuang X, An W, Liu C, Liu Y, Liu S, He R, Wang H, Qi X*. Diagnosis of Clinically Significant Portal Hypertension Using CT- and MRI-based Vascular Model. Radiology. 2023 Jan 31:221648. doi: 10.1148/radiol.221648. (senior author) 

10. Du X#, Wei L#, Yang B, Long S, Wang J, Sun A, Jiang Y, Qiao Z, Wang H*, Wang Y*. Cortical and subcortical morphological alteration in Angelman syndrome. J Neurodev Disord. 2023 Feb 14;15(1):7.

11. Sun A#, Zhao B#, Zheng Y, Long Y, Wu P, Wang B, Li R, Wang H*. Motion-resolved real-time 4D flow MRI with low-rank and subspace modeling. Magn Reson Med. 2023 May;89(5):1839-1852.

12. Wu Y#, Ke J#, Ye S, Shan LL, Xu S, Guo SF, Li MT, Qiao TC, Peng ZY, Wang YL, Liu MY, Wang H*, Feng JF*, Han Y*. 3D Visualization of Whole Brain Vessels and Quantification of Vascular Pathology in a Chronic Hypoperfusion Model Causing White Matter Damage. Transl Stroke Res. 2023 May 24. doi: 10.1007/s12975-023-01157-1. 

13. Sun CC#, Zhang YW#, Xing XX#, Yang Q, Cao LY, Cheng YF, Zhao JW, Zhou ST, Cheng DD, Zhang Y, Hua XY*, Wang H*, Xu DS*. Modified constraint-induced movement therapy enhances cortical plasticity in a rat model of traumatic brain injury: a resting-state functional MRI study. Neural Regen Res. 2023 Feb;18(2):410-415.

14. Dai Y, Wang C, Wang H*. Deep compressed sensing MRI via a gradient-enhanced fusion model. Med Phys. 2023 Jan 25. doi: 10.1002/mp.16164.

15. Wu S#, Yu H#, Li C, Zheng R, Xia X, Wang C*, Wang H*. A Coarse-to-Fine Fusion Network for Small Liver Tumor Detection and Segmentation: A Real-World Study. Diagnostics (Basel). 2023 Jul 27;13(15):2504.

16. Xu J, Zhang Y, Liu Y, You Y, Li F, Chen Y, Xie L, Tong S, Zhou S, Liang K, Huang Y, Jiang G, Song Q, Mei N, Ma F, Gao X*, Wang H*, Chen J*. Vitality-Enhanced Dual-Modal Tracking System Reveals the Dynamic Fate of Mesenchymal Stem Cells for Stroke Therapy. Small. 2022 Nov;18(47):e2203431. doi: 10.1002/smll.202203431. 

17. Xue X#, Zhang Y#, Tao W, Wei L, Li Q, Ma T, Xu X, Wang Y, Gu X, Xu Z, Wang H*, Hua Y*. Longitudinal neuroplasticity after ankle sprain in mice: A voxel-based morphometry study on 11.7T MRI. J Orthop Res. 2022 Oct 6. doi: 10.1002/jor.25458.

18. Xue X#, Li Q#, Wang Y#, Lu R, Han J, Zhang H, Xu X, Tao W, Ma T, Li Y, Wang H*, Hua Y*. Impaired corticospinal tract in chronic ankle instability: A diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI) study at 7.0 Tesla. J Sci Med Sport. 2022 Aug;25(8):649-654.

19. Wang Y, Li Q, Xue X, Xu X, Tao W, Liu S, Li Y, Wang H*, Hua Y*. Neuroplasticity of pain processing and motor control in CAI patients: A UK Biobank study with clinical validation. Front Mol Neurosci. 2023 Feb 14;16:1096930. doi: 10.3389/fnmol.2023.1096930.

20. Xue X#, Lu R#, Zang DI, Li H, Zhang H, Xu H, Li Q, Ma T, Tang W, Chen S, Wang H, Hua Y. Low Regional Homogeneity of Intrinsic Cerebellar Activity in Ankle Instability: An Externally Validated rs-fMRI Study. Med Sci Sports Exerc. 2022 Dec 1;54(12):2037-2044.

21. Wang FW#, Zhang H#, Dai F, Chen WB, Xu S, Yang ZD, Shen DG, Wang CY*, Wang H*. Multiple B-Value Model-Based Residual Network (MORN) for Accelerated High-Resolution Diffusion-Weighted Imaging. IEEE J Biomed Health Inform. 2022 Jul 25;PP. doi: 10.1109/JBHI.2022.3193299. 

22. Wei L#*, Ding M#, Zhang YW, Wang H*. Decoding transcriptional signatures of the association between free water and macroscale organizations in healthy adolescents. Neuroimage. 2022; doi: https://doi.org/10.1016/j.neuroimage.2022.119514.

23. Zhang BY, Yang ZD, Li J, Wang B, Shi HZ, Wang H*, Li YH*. Modification of cerebrovascular morphologies during different stages of life. J Cereb Blood Flow Metab. 2022 Jul 1:271678X221111609. doi: 10.1177/0271678X221111609. 

24. Wang LL#, Wang CY#, Wang FW, Chu YH, Yang ZD, Wang H*. EPI Phase Error Correction with Deep Learning (PEC-DL) at 7T. Magn Reson Med. 2022; doi: 10.1002/mrm.29317.

25. Xu J#, Ren Y#, Zhao X, Wang X, Yu X, Yao Z, Zhou Y, Feng X, Zhou XJ, Wang H*. Incorporating multiple magnetic resonance diffusion models to differentiate low- and high-grade adult gliomas: a machine learning approach. Quant Imaging Med Surg. 2022 Nov;12(11):5171-5183.

26. Zhang J, Zhao H, Xue Y, Liu Y, Fan G, Wang H*, Dong Q*, Cao W*. Impaired Glymphatic Transport Kinetics Following Induced Acute Ischemic Brain Edema in a Mouse pMCAO Model. Front Neurol. 2022 Mar 17;13:860255. doi: 10.3389/fneur.2022.860255.

27. Zhang H#, Wang C#, Chen W, Wang F, Yang Z, Xu S, Wang H*. Deep Learning based Multiplexed Sensitivity-encoding (DL-MUSE) for High-resolution Multi-shot DWI. Neuroimage. 2021; doi: 10.1016/j.neuroimage.2021.118632. 

28. Zeng R, Lv J, Wang H, Zhou L, Barnett M, Calamante F*, Wang C*. FOD-Net: A deep learning method for fiber orientation distribution angular super resolution. Med Image Anal. 2022 Apr 6;79:102431. doi: 10.1016/j.media.2022.102431. 

29. Yan M#, Yu W#, Lv Q, Lv Q, Bo T, Chen X, Liu Y, Zhan Y, Yan S, Shen X, Yang B, Hu Q, Yu J, Qiu Z, Feng Y, Zhang XY, Wang H, Xu F, Wang Z*. Mapping brain-wide excitatory projectome of primate prefrontal cortex at submicron resolution and comparison with diffusion tractography. Elife. 2022 May 20;11:e72534. doi: 10.7554/eLife.72534. 

30. Wang CY#, Shi Z#, Yang M, Huang LX, Fang WX, Jiang L, Ding J*, Wang H*. Deep Learning-based identification of acute ischemic core and deficit from non-contrast CT and CTA. J Cereb Blood Flow Metab. 2021; doi:10.1177/0271678X211023660. 

31. Yuan S#, Liao G#, Zhang M#, Zhu Y#, Xiao W#, Wang K, Li C, Jia C, Sun N, Walch A, Gao D, Xu P*, Deng Q*, Zhang J*, Wang H*, Hu R*. Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV. Cell Discov. 2021 Nov 2;7(1):105. doi: 10.1038/s41421-021-00337-3. 

32. Guo L#, Wang H#, Zhou J, Tang W, Wang R, Xiao Z, Wu L, Wang J, Li L, Lei Y*, Sun X*, Tang Z*. Magnetic resonance imaging investigations reveal that PM2.5 exposure triggers visual dysfunction in mice. Ecotoxicol Environ Saf. 2021 Oct 8;227:112866. doi: 10.1016/j.ecoenv.2021.112866. 

33. Su J#, Ni W#, Yang B, Xiao W, Gao X, Yang H, Li Y, Lei Y, Jiang H, Wang H*, Gu Y, Mao Y*. Preliminary Study on the Application of Ultrahigh Field Magnetic Resonance in Moyamoya Disease. Oxid Med Cell Longev. 2021 Jan 13;2021:5653948. doi: 10.1155/2021/5653948. 

34. Wang KX, Wang S, Xiong MH, Wang CY*, Wang H*. Non-invasive Assessment of Hepatic Venous Pressure Gradient (HVPG) Based on MR Flow Imaging and Computational Fluid Dynamics. MICCAI 2021, LNCS 12907, pp.1-10, 2021.

35. Huang X#, Lin C#, Luo C, Guo Y, Li J, Wang Y, Xu J, Zhang Y, Wang H* , Liu Z*, Chen B*. Fe3O4@M nanoparticles for MRI-targeted detection in the early lesions of atherosclerosis. Nanomedicine. 2021 Apr;33:102348. doi: 10.1016/j.nano.2020.102348.

36. Liu Q#, Zhang B#, Wang L, Zheng R, Qiang J, Wang H*, Yan F*, Li R*. Assessment of Vascular Network Connectivity of Hepatocellular Carcinoma Using Graph-Based Approach. Front Oncol. 2021 Jul 6;11:668874. doi: 10.3389/fonc.2021.668874.

37. Xia BQ#, Wang H#, Wang Z, Qian ZX, Xiao Q, Liu Y, Shao ZM, Zhou SL, Chai WM, You C*, Gu YJ*. A Combined Nomogram Model to Predict Disease-free Survival in Triple-Negative Breast Cancer Patients with Neoadjuvant Chemotherapy. Front Genet. 2021 Nov 21; doi: 10.3389/fgene.2021.783513.

38. Wang C*, Li Y, Lv J, Jin J, Hu X, Kuang X, Chen W, Wang H*. Recommendation for Cardiac Magnetic Resonance Imaging-Based Phenotypic Study: Imaging Part. Phenomics. 2021;1(4):151-170.

39. Huang Y#, Xiao Q#, Sun Y, Wang Z, Li Q, Wang H*, Gu Y*. An Approach Based on Mammographic Imaging and Radiomics for Distinguishing Male Benign and Malignant Lesions: A Preliminary Study. Front Oncol. 2021 Feb 16;10:607235. doi: 10.3389/fonc.2020.607235.

40. Tang YM#, Yao Y#, Xu S, Li X, Hu F, Wang H*, Ding J*, Wang X. White Matter Microstructural Damage Associated With Gait Abnormalities in Idiopathic Normal Pressure Hydrocephalus. Front Aging Neurosci. 2021 Aug 9;13:660621. doi: 10.3389/fnagi.2021.660621.

41. Li Q#, Xiao Q#, Li J, Wang Z, Wang H*, Gu Y*. Value of Machine Learning with Multiphases CE-MRI Radiomics for Early Prediction of Pathological Complete Response to Neoadjuvant Therapy in HER2-Positive Invasive Breast Cancer. Cancer Manag Res. 2021 Jun 28;13:5053-5062. 

42. Zhang B#, Wang Y#, Wang B#, Chu YH, Jiang Y, Cui M*, Wang H*, Chen X*. MRI-Based Investigation of Association Between Cerebrovascular Structural Alteration and White Matter Hyperintensity Induced by High Blood Pressure. J Magn Reson Imaging. 2021 Jun 28. doi: 10.1002/jmri.27815.

43. Shi Z#, Li J#, Zhao M#, Zhang M, Wang T, Chen L, Liu Q, Wang H*, Lu J*, Zhao X. Baseline Cerebral Ischemic Core Quantified by Different Automatic Software and Its Predictive Value for Clinical Outcome. Front Neurosci. 2021 Apr 12;15:608799. doi: 10.3389/fnins.2021.608799. PMID: 33911999.

44. Zheng R#, Wang L#, Wang C, Yu X, Chen W, Li Y, Li W, Yan F, Wang H*, Li R*. Feasibility of automatic detection of small hepatocellular carcinoma (≤2 cm) in cirrhotic liver based on pattern matching and deep learning. Phys Med Biol. 2021 Mar 29. doi: 10.1088/1361-6560/abf2f8. Epub ahead of print. PMID: 33780910.

45. Zheng R#, Shi C#, Wang C, Shi N, Qiu T, Chen W, Shi Y*, Wang H*. Imaging-Based Staging of Hepatic Fibrosis in Patients with Hepatitis B: A Dynamic Radiomics Model Based on Gd-EOB-DTPA-Enhanced MRI. Biomolecules. 2021 Feb 18;11(2):307. doi: 10.3390/biom11020307. PMID: 33670596; PMCID: PMC7922315.

46.  Zhao X#, Shi J#, Dai F, Wei L, Zhang B, Yu X, Wang C, Zhu W*, Wang H*. Brain Development From Newborn to Adolescence: Evaluation by Neurite Orientation Dispersion and Density Imaging. Front Hum Neurosci. 2021 Mar 15;15:616132. doi: 10.3389/fnhum.2021.616132.

47. Wang F, Zhang H, Dai F, Chen W, Wang C*, Wang H*. MAGnitude-Image-to-Complex K-space (MAGIC-K) Net: A Data Augmentation Network for Image Reconstruction. Diagnostics (Basel). 2021 Oct 19;11(10):1935. doi: 10.3390/diagnostics11101935.

48.  Wang Y#, Jiang L#, Zhang Y, Lu Y, Li J, Wang H*, Yao D*, Wang D*. Fibronectin-Targeting and Cathepsin B-Activatable Theranostic Nanoprobe for MR/Fluorescence Imaging and Enhanced Photodynamic Therapy for Triple Negative Breast Cancer. ACS Appl Mater Interfaces. 2020 Jul 29;12(30):33564-33574. 

49.  Wei L#, Han X#, Sun YW, Ding M, Du YS, Jiang WQ, Zhou Yan*, Wang H*. Brain controllability and morphometry similarity of internet gaming addiction. Methods. 2020; S1046-2023(20)30163-8.

50. Chen KL#, Zhao GX#, Wang H#, Wei L, Huang YY, Chen SD, Lin BY, Dong Q, Cui M, Yu, JT*. A novel de novo RNF216 mutation associated with autosomal recessive Huntington-like disorder. Ann Clin Transl Neurol. 2020; DOI: 10.1002/acn3.51047.

51. Meng XF#, Zhang BY#, Yi Y, Cheng Hui, Wang BM, Liu YY, Gong T, Yang W, Yao YF, Wang H*, Bu WB*. Accurate and Real-Time Temperature Monitoring during MR Imaging Guided PTT. Nano Letters. 2020; DOI: 10.1021/acs.nanolett.9b05267. 

52. Wang Q#, Xiao H#, Yu X, Lin H, Yang B, Zhang Y, Feng D, Yan F*, Wang H*. R1ρ at high spin-lock frequency could be a complementary imaging biomarker for liver iron overload quantification. Magn Reson Imaging. 2021;75:141-148.

53. Zhang TT, Lu YM, Yang BF, Zhang CY, Li JN, Liu HH, Wang H*, Wang DB*. Diffusion Metrics for Staging Pancreatic Fibrosis and Correlating with Epithelial-Mesenchymal Transition Markers in a Chronic Pancreatitis Rat Model at 11.7T MRI. J Magn Reson Imaging. 2019; DOI: 10.1002/jmri.26995.

54. Wang H*, Zheng RC, Dai F, Wang QF, Wang CY*. High-field MR Diffusion-weighted Image Denoising Using a Joint Denoising Convolutional Neural Network. J Magn Reson Imaging. 2019;50(6):1937-1947.

55. Xie TW#, Wang Z#, Zhao QF, Bai QM, Zhou XY, Gu YJ, Peng WJ*, Wang H*. Machine Learning-Based Analysis of MR Multiparametric Radiomics for the Subtype Classification of Breast Cancer. Front Oncol. 2019; DOI: 10.3389/fonc.2019.00505.

56. Yang M, Yan Y, Wang H*. IMAge/enGINE: a freely available software for rapid computation of high-dimensional quantification. Quant Imaging Med Surg. 2019;9(2):210-218.

57. Feng R, Zhao J, Wang H, Yang B, Feng J, Shi Y, Zhang M, Liu C, Zhang Y, Zhuang J, Wei H*. MoDL-QSM: Model-based deep learning for quantitative susceptibility mapping. Neuroimage. 2021 Oct 15;240:118376. doi: 10.1016/j.neuroimage.2021.118376. 

58. Liu Z#, Rolls ET#, Liu Z#, Zhang K, Yang M, Du J, Gong W, Cheng W, Dai F, Wang H, Ugurbil K, Zhang J*, Feng J*. Brain annotation toolbox: exploring the functional and genetic associations of neuroimaging results. Bioinformatics. 2019 Oct 1;35(19):3771-3778.

 

二、 近五年申请专利：

1.       一种基于磁共振指纹的动态增强磁共振成像方法：赵雪莹（学生），王鹤，张博宇。201810241545.X（已授权并转化,20万）

2.       一种基于神经网络的多次激发平面回波磁共振成像方法：张会（博士后）、王鹤。202011458419.3（已授权并转化,55万）

3.       脑血管形态特征定量分析方法：王鹤、张博宇。202110106311.6（已授权并转化,55万）

4.       基于7.0T磁共振成像系统的头/膝关节多用途射频线圈装置：王鹤、方磊。202011458436.7（已授权）

5.       一种基于磁共振指纹成像的快速定量T1ρ的方法：王前锋（助理）、王鹤、戴飞。202010400589.X（已授权）

6.       一种基于深度学习的多模态肝脏磁共振影像配准系统：于航（学生）、王成彦、王鹤。202010845127.9（已授权）

7.       一种磁共振肝癌疗效评估方法和系统：张博宇（学生），王鹤，赵雪莹。201810241827.X

8.       一种肺部CT与MRI影像融合算法：郑忍成（学生），王鹤，单飞，杨舒一，施裕新。201811575740.2（已授权）

9.       一种基于影像组学分析的MRI影像肝纤维化自动分级方法：王鹤、郑忍成、单飞、施裕新。201911056189.5（已授权）

10.  一种基于单次激发的弥散加权成像扫描重建方法与系统；王鹤、王繁文、王成彦。202111216100.4（已授权）

11.  肝静脉压力梯度的测量方法、测量系统、电子设备及介质。王成彦，王可欣，王鹤。202110773265.5

12.  一种无外加门控的五维血流磁共振成像方法；孙爱琦、王鹤。202210626697.8

13.  一种基于深度学习的EPI相位矫正：王丽丽（助理）、王鹤、王成彦。202111262206.8

14.  一种针对四维血流磁共振成像的速度解卷绕方法：王鹤、孙爱琦、王冰怡、刘颖。2023101746634

15.  一种基于深度学习的3T MRA到7T MRA的预测方法：王鹤、汤玮、王成彦。202310719567.3

 

三、 近五年软著：

1.  磁共振高分辨弥散加权成像数据重建后处理软件，张会、王鹤。2021SR1936501

2.  磁共振体素内不相干运动数据后处理平台使用软件，王丽丽、王鹤。2021SR1936502

 

四、 学术奖励：

1.  2023年度上海市科技进步二等奖（排名第一）：《基于影像的脑血管病精准诊疗关键技术及应用》

2.  2022年度江西省科技进步二等奖（排名第二）：《缺血性脑卒中智能辅助诊疗技术及决策系统构建与推广应用》

3.  第十六届上海中西医结合科技奖二等奖（排名第二）：《中西医结合小血管病异病同治的疗效与机制研究》