王鹤

个人信息Personal Information

教师拼音名称:Wang He

电子邮箱:hewang@fudan.edu.cn

所在单位:类脑智能科学与技术研究院

学历:研究生毕业

学位:博士学位

职称:研究员

在职信息:在职

毕业院校:华东师范大学

博士生导师

硕士生导师

学科:生物医学工程

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成果

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部分SCI论文:

  1. Wang CY#, Shi Z#, Yang M, Huang LX, Fang WX, Jiang L, Ding J*, Wang H*. Deep Learning-based identification of acute ischemic core and deficit from non-contrast CT and CTA. J Cereb Blood Flow Metab. 20212021; doi:10.1177/0271678X211023660.

  2. Zheng R#, Wang L#, Wang C, Yu X, Chen W, Li Y, Li W, Yan F, Wang H*, Li R*. Feasibility of automatic detection of small hepatocellular carcinoma (≤2 cm) in cirrhotic liver based on pattern matching and deep learning. Phys Med Biol. 2021 Mar 29. doi: 10.1088/1361-6560/abf2f8. Epub ahead of print. PMID: 33780910.

  3. Shi Z#, Li J#, Zhao M#, Zhang M, Wang T, Chen L, Liu Q, Wang H*, Lu J*, Zhao X. Baseline Cerebral Ischemic Core Quantified by Different Automatic Software and Its Predictive Value for Clinical Outcome. Front Neurosci. 2021 Apr 12;15:608799. doi: 10.3389/fnins.2021.608799. PMID: 33911999.

  4. Zheng R#, Shi C#, Wang C, Shi N, Qiu T, Chen W, Shi Y*, Wang H*. Imaging-Based Staging of Hepatic Fibrosis in Patients with Hepatitis B: A Dynamic Radiomics Model Based on Gd-EOB-DTPA-Enhanced MRI. Biomolecules. 2021 Feb 18;11(2):307. doi: 10.3390/biom11020307. PMID: 33670596; PMCID: PMC7922315.

  5. Zhao X#, Shi J#, Dai F, Wei L, Zhang B, Yu X, Wang C, Zhu W*, Wang H*. Brain Development From Newborn to Adolescence: Evaluation by Neurite Orientation Dispersion and Density Imaging. Front Hum Neurosci. 2021 Mar 15;15:616132. doi: 10.3389/fnhum.2021.616132. PMID: 33790750; PMCID: PMC8005551.

  6. Wang Y#, Jiang L#, Zhang Y, Lu Y, Li J, Wang H*, Yao D*, Wang D*. Fibronectin-Targeting and Cathepsin B-Activatable Theranostic Nanoprobe for MR/Fluorescence Imaging and Enhanced Photodynamic Therapy for Triple Negative Breast Cancer. ACS Appl Mater Interfaces. 2020 Jul 29;12(30):33564-33574.

  7. Wei L#, Han X#, Sun YW, Ding M, Du YS, Jiang WQ, Zhou Yan*, Wang H*. Brain controllability and morphometry similarity of internet gaming addiction. Methods. 2020; S1046-2023(20)30163-8.

  8. Wang QF#, Xiao H#, Yu XC, Lin HM, Yang BF, Zhang YW, Feng DY, Yan FH*, Wang H*. R1ρ at high spin-lock frequency could be a complementary imaging biomarker for liver iron overload quantification. Magn Reson Imaging. 2020; DOI: 10.1016/j.mri.2020.10.01.

  9. Chen KL#, Zhao GX#, Wang H#, Wei L, Huang YY, Chen SD, Lin BY, Dong Q, Cui M, Yu, JT*. A novel de novo RNF216 mutation associated with autosomal recessive Huntington-like disorder. Ann Clin Transl Neurol. 2020; DOI: 10.1002/acn3.51047.

  10. Meng XF#, Zhang BY#, Yi Y, Cheng Hui, Wang BM, Liu YY, Gong T, Yang W, Yao YF, Wang H*, Bu WB*. Accurate and Real-Time Temperature Monitoring during MR Imaging Guided PTT. Nano Letters. 2020; DOI: 10.1021/acs.nanolett.9b05267.

  11. Xie TW#, Wang Z#, Zhao Qf, Bai QM, Zhou XY, Gu YJ, Peng WJ*, Wang H*. Machine Learning-Based Analysis of MR Multiparametric Radiomics for the Subtype Classification of Breast Cancer. Frontiers in Oncology. 2019; doi: 10.3389/fonc.2019.00505.

  12. Wang H*, Zheng RC, Dai F, Wang QF, Wang CY*. High-field mr diffusion-weighted image denoising using a joint denoising convolutional neural network. J Magn Reson Imaging. 2019; doi: 10.1002/jmri.26761.

  13. Zhang TT#, Lu YM#, Yang BF, Zhang CY, Li JN, Liu HH, Wang H*, Wang DB*. Diffusion Metrics for Staging Pancreatic Fibrosis and Correlating With Epithelial-Mesenchymal Transition Markers in a Chronic Pancreatitis Rat Model at 11.7T MRI. J Magn Reson Imaging. 2019; DOI: 10.1002/jmri.26995.

  14. Yang M, Yan Y, Wang H*. IMAge/enGINE: a freely available software for rapid computation of high-dimensional quantification. Quant Imaging Med Surg. 2019;9(2):210-218.

  15. Liu ZW, Rolls E, Liu Z, Zhang K, Du J, Yang M, Gong WK, Cheng W, Dai F, Wang H, Ugurbil K, Zhang J, Feng JF. Brain annotation toolbox: exploring the functional and genetic associations of neuroimaging results. Bioinformatics. 2019;doi: 10.1093/bioinformatics/btz128.

  16. Ping W, Mao L, Yin D, Sun W, Wang H, Zhang Q, Wang J, Chen C, Zeng M, Ding J, Wang X. Functional network changes in the hippocampus contribute to depressive symptoms in epilepsy. Seizure: European Journal of Epilepsy. 2018;60:16-22.

  17. Chen S, Ji X, Liu M, Xia Z, Zheng H, Yin Q, Wang H*, Li Y*. The value of MRI in evaluating the efficacy and complications with the treatment of intra-arterial chemotherapy for retinoblastoma. Oncotarget. 2017;13:38413-25.

  18. Wang C, Zhang R, Zhang X, Wang H, Zhao K, Jin L, Zhang J, Wang X, Fang J. Simultaneous dynamic R2 R2′, and R2* measurement using periodic π pulse shifting multiecho asymmetric spin echo sequence moving estimation strategy: A feasibility study for lower extremity muscle. Magn Reson Med. 2017;77:766-73.

  19. MM. Karaman, H. Wang, Y. Sui, HH. Engelhard, YH. Li, XJ. Zhou. A fractional motion diffusion model for grading pediatric brain tumors. NeuroIamge: Clinical. 2016;12:707-14.

  20. Wang C, Zhang R, Wang R, Jiang L, Zhang X, Wang H, Zhao K, Jin L, Zhang J, Wang X, Fang J. Noninvasive measurement of renal oxygen extraction fraction under the influence of respiratory challenge. J Magn Reson Imaging. 2016;44:230-37.

  21. Wang C, Zhao K, Zhang R, Jiang L, Wang R, Zhang X, Wang H, Jin L, Zhang J, Wang X, Fang J. Evaluation of renal oxygenation change under the influence of carbogen breathing using a dynamic R2 , R2 ‘ and R2 * quantification approach. NMR Biomed. 2016;29:1601-07.

  22. Y. Sui, H. Wang, GZ. Liu, FW. Damen, C. Wanamaker, YH. Li, XH. Zhou. Differentiation of Low- and High-Grade Pediatric Brain Tumors with High b-Value Diffusion-weighted MR Imaging and a Fractional Order Calculus Model. Radiology, 2015.

  23. CY. Wang, R. Zhang, XD. Zhang, H. Wang, K. Zhao, LX. Jin, J. Zhang, XY. Wang, J. Fang. Noninvasive Measurement of Lower Extremity Muscle Oxygen Extraction Fraction under Cuff Compression Paradigm. J Magn Reson Imaging, 2015.

  24. K. M, Y. Sui, H. Wang, RL. Magin, YH. Li, XH. Zhou. Differentiating Low- and High-Grade Pediatric Brain Tumors Using a Continuous-Time Random-Walk Diffusion Model at High b-Values. Magn Reson Med, 2015.

  25. ST. Suo, KB. Zhang, MQ. Cao, XS. Suo, JH. Hua, XC. Geng, J. Chen, ZG. Zhuang, X. Ji, Q. Lu, H. Wang, JR. Xu. Characterization of breast masses as benign or malignant at 3.0T MRI with whole-lesion histogram analysis of the apparent diffusion coefficient. J Magn Reson Imaging, 2015.

  26. JL. Gao, ST. Feng, BX. Wu, NJ. G, MH. L, PM. Wu, H. Wang, XM. He, BS. H. Microstructural Brain Abnormalities of Children of Idiopathic Generalized Epilepsy With Generalized Tonic-Clonic Seizure: A Voxel-Based Diffusional Kurtosis Imaging Study. J Magn Reson Imaging, 2015.

  27. D. Wang, ZH. Guo, XH. Liu, YH. Li, H. Wang. Examination of hippocampal differences between Alzheimer disease, amnestic mild cognitive impairment and normal aging: diffusion kurtosis. Curr Alzheimer Res, 2015.

  28. ST. Suo, N. Lin, H. Wang, LB. Zhang, R. Wang, S. Zhang, J. Hua, JR. Xu. Introvoxel incoherent motion diffusion-weighted MR imaging of cancer at 3.0 tesla: comparison of diffusion curve-fitting methods. J Magn Reson Imaging, 2015.

  29. C. Ma, L. Liu, YJ. LI, LG. Chen, CS. Pan, Y. Zhang, H. Wang, SY. Chen, JP. Lu. Intravoxel incoherent motion MRI of the healthy pancreas: Monoexponential and biexponential apparent diffusion parameters of the normal head, body and tail, J Magn Reson Imaging, 2014.

  30. C. Ma, YJ. LI, LG. CS. Pan, H. Wang, J. Wang, SY. Chen, JP. Lu. High resolution diffusion weighted magnetic resonance imaging of the pancreas using reduced field of view single-shot echo-planar imaging at 3 T. Magn Reson Imaging, 2014.

  31. J. Zhang, L. Chen, H. Wang, et al. High-spatial-resolution isotropic three-dimensional fast-recovery fast spin-echo magnetic resonance dacryocystography combined with topical administration of sterile saline solution, European J Radiology, 2013.

  32. L. Li, L. Wang, Z. Feng, Z. Hu, G. Wang, X. Yuan, H. Wang, D. Hu. Prostate cancer magnetic resonance imaging (MRI): multidisciplinary standpoint. Quant Imaging Med Surg, 2013.

  33. C. Ma, CS. Pan, HG. Zhang, H. Wang, J. Wang, SY. Chen, JP. Lu. Diffusion-weighted MRI of the normal adult pancreas: The effect of age on apparent diffusion coefficient values. Clinical Radiology, 2013.

部分国际会议摘要:

  1. Zhang H, Xu JQ, Yu XC, Chen WB, Wang CY, Wang H.Deep learning based high resolution IVIM parameter mapping in lacunar infarction patients. ISMRM, 2021.

  2. Dai YX, Wang CY, Wang H. Compressed sensing MRI via a fusion model based on image and gradient priors. ISMRM,2021.

  3. Yu XC,Han JW,He M,Chen WB,Ding J,Wang H. Differential cognitive impairment of lateral ventricle small infarct: Brain atrophy and blood oxygen activity under the cortical layer. ISMRM,2021.

  4. Wang QF, Wang H, Feng DY. The feasibility of T1ρ magnetic resonance fingerprinting with a random design at 11.7T. ISMRM 2021.

  5. Wang QF, Xiao H, Yu XC, Wang H, and Yan FH. Comparison of T1ρ imaging between rapid acquisition with relaxation enhancement (RARE) and ultrashort TE (UTE) sequence of rat liver at 11.7T MRI. ISMRM 2021.

  6. Wang QF, Xiao H, Wang H, and Yan FH. Ultrashort echo time R1ρ for detection of rat liver iron overload at 11.7T MRI. ISMRM 2021.

  7. Wei L, Ding M, Xiao X, Wang H. Regional brain MRI features reveal the histological alterations in chronic pain: an MRI-based cell imaging study. ISMRM,2021.

  8. Han JW, Zhang H, Xu JQ, Wang FW, Gao J, Chen WB, Yan HM, Wang H. Changes in Gray Matter Volume and Functional Connectivity of Obese Females with Acupuncture and Diet Control Therapy: Placebo Effect or Not? ISMRM,2021.

  9. Zheng RC, Wang LN, Wang CY, Yu XC, Chen WB, Li Y, Li WX, Yan FH, Wang H, Li RK. Automatic Detection of Small Hepatocellular Carcinoma (≤2 cm) in Cirrhotic Liver based on Pattern Matching and Deep Learning. ISMRM, 2021.

  10. Wang FW, Zhang H, Dai F, Chen WB, Wang CY, Wang H. Simultaneous Reconstruction of high-resolution multi b-value DWI using one-shot. ISMRM, 2021.

  11. Wang FW, Zhang H, Han JW, Dai F, Dai YX, Chen WB, Wang CY, Wang H.  MAGnitude Image to Complex(MAGIC)-Net: reconstructing multi-coil complex images with pre-trained network using synthesized raw data. ISMRM,2021.

  12. Wang CY, Li Y, Lv J, Li B, Dai F, Chen WB, Wang H. Calibrationless SENSE Reconstruction with Deep Coil Sensitivity Learning. ISMRM, 2020.

  13. Xu S, Yao Y, Ding J, Wang H. Gait – related white matter tracts damage in idiopathic normal pressure hydrocephalus. ISMRM, 2020.

  14. Wang LL, Wang FW, Chu YH, Yu XC, Wang CY, Wang H. EPI Phase correction using model-based deep learning reconstruction. ISMRM, 2020.

  15. Wang QF, Xiao H, Wang H, Yu XC, Yan FH. T1ρ could be a complementary tool for T2* in the assessment of rat liver iron overload. ISMRM, 2020.

  16. Wei L, Chen KL, Wang H. The white matter impairment of Gordon-Holmes syndromes: a tracking based analysis. ISMRM, 2020.

  17. Xu JQ, Wang H, Zhao XY, Zhang H, Feng XY, Ren Y. Differentiating Low- and High-Grade Adult glioma Using Multi-diffusion Models. ISMRM, 2020.

  18. Zhang BY, Wang B, Wang CY, Chu YH, Wang H. Cerebrovascular Atlas: A Novel Framework to Detect Structural Alterations Using MRA. ISMRM, 2020.

  19. Zhang H, Feng ZY, Chen WB, Wang YS, Wang CY, Wang H. Incorporating Deep Learning into Multi-shot EPI DWI Reconstruction. ISMRM, 2020.

  20. Zhao XY, Chu YH, Wang QF, Wang H. Quantitative Tracking of T1 and T2* in DCE-MRI by Dynamic MR Fingerprinting. ISMRM, 2020.

  21. Hsu YC, Wang H, Chu YH. Near bias-free robust MP2RAGE reconstruction using a signal-dependent regularization function. ISMRM, 2020.

  22. Zheng RC, Wang QD, Feng ZY, Wang CY, Wang H. Automatic Liver Tumor Detection using Deep learning based segmentation and Radiomics guided Candidate Filtering. ISMRM, 2020.

  23. Zhao XY, Wang, H. Atlas-based analysis of brain development from newborn to adolescence using NODDI. ISMRM, 2019.

  24. Zhao XY, Wang, H. A cluster-based diffusion spectrum analysis of diffusion-attenuated signal in glioma. ISMRM, 2019.

  25. Wei L, Wang H. The gray matter volume and shape abnormal in angelman syndromes. ISMRM, 2019.

  26. Wang Z, Wang H. Radiomics Signature on preoperative MR imaging:To predict pathological complete response and disease-free survival in patientes with Triple-negative breast cancer(TNBC) to neoadjuvant chemotherapy (NAC) . ISMRM, 2019.

  27. Wang CY, Gao F, Kong HJ, Jiang Li, Huang WJ, Wang R, Zhao K, Jia Y, Xu H, Wang H, Zhang XD, Yang L, Zhang J, Wang XY, Fang J. A feasibility study of using noninvasive renal oxygenation imaging to delineate different severities of renal ischemia in atheroembolic renal disease model. ISMRM, 2017.

  28. Wang CY, Zhang BH, Wang HC, Kong HJ, Gao F, Jiang L, Wang H, Zhang XD, Yang M, Zhang J, Wang XY, Fang J. Hemodynamic response to respiratory challenge evaluated by dynamic R2’ imaging: application for acute renal ischemia caused by microsphere-induced renal artery embolism. ISMRM, 2017.

  29. Wang CY, Jiang L, Kong HJ, Gao F, Huang WJ, Wang R, Ding L, Jia Y, Xu H, Wang H, Zhang XD, Yang L, Zhang J, Wang XY, Fang J. Targeted-FOV DWI can better depict the microemboli-induced renal lesions comparing to conventional full-FOV DWI. ISMRM, 2017.

  30. Wang CY, Kong HJ, Gao F, Huang WJ, Ding L, Wang R, Liang L, Jia Y, Xu H, Wang H, Zhang XD, Yang L, Zhang J, Wang XY, Fang J. Comparison of BOLD-contrast imaging and DW imaging for early prediction of renal damage after microemboli-induced acute kidney injury in animal model. ISMRM, 2017.

  31. Karaman MM, Xiong Y, Wang H, Damen FC, Li YH, Zhou XJ. Fractional Motion Diffusion Model for Differentiation of Low- and High-Grade Pediatric Brain Tumors. ISMRM, 2016.

  32. Wang CY, Zhang R, Li J, Wang R, Zhang XD, Wang H, Zhao K, Jin LX, Zhang J, Wang XY, Fang J. MRI-based Evaluation of Renal Oxygenation Under the Influence of Carbogen Breathing. ISMRM, 2016.

  33. Wang H, Shi KN, Chen WB, Wang GL. Improving the quality of the multi-b diffusion weighted images using the intrinsic multi-exponential pattern. ISMRM, 2016.

  34. Feng Y, Wang H, Li JB. A 3D non-rigid registration method for liver in DCE MR images. ISMRM, 2016.

  35. Chen WB, Chen X, Wang GB, Chan Q, Wang H, Li JQ, Li XZ, Wang SS, Yao B, Xu DR. Quantitative 3D Whole Liver T1rho Mapping at 3.0T. ISMRM, 2015.

  36. Wang CY, Zhang R, Zhang XD, Wang H, Zhao K, Zhang J, Wang XY, Fang J. Skeletal muscle oxygen extraction fraction measurement – at rest and during ischemia. ISMRM, 2015.

  37. Shi KN, Wang H, Cao G, Qi Y, Wang XM. A Time efficient IVIM analysis method using fuzzy clustering algorithm. ISMRM, 2015.

  38. Wang XY, Zhang R, Zhang XD, Wang H, Zhao K, Zhang J, Wang XY, Fang J. Dynamic measurement of muscle R2, R2′ and R2* during ischemia and reactive hyperemia. ISMRM, 2015

  39. Wang H, Zhu NY, Yan FH, Cao G, Yan X. Correlation Study of Quantitative Diffusional Kurtosis Imaging with Serum Indicators in Liver Fibrosis, ISMRM, 2013.

  40. Wang H, Cao G, Li YH, Duan XJ. Evaluation of Multi-component Diffusion Coeffcients in Pediatric Gliomas, ISMRM, 2013.

  41. Wang H, Ma C, Chen NK, Lu JP, Song A, Cao G. Cervical Spine DWI using Reduced-FOV Multi-shot EPI with 2D Phase Cycling Reconstruction, ISMRM, 2013.

  42. Li YJ, Ma C, Wang H, Chen SY, Lu JP. High Resolution Diffusion Weighted Imaging of Pancreatic adenocarcinoma using 2D Reduced Field of View Single-Shot Echo-planar Imaging at 3.0 Tesla, ISMRM, 2013.

  43. Mu KT, Qin YY, Zhang Y, Wang H, Zhu WZ. EGFR MAb-bioconjugated superparamagnetic iron oxide nanoparticles as a specific MRI contrast agent for detection of brain glioma in vivo, ISMRM, 2013.

  44. Li QX, Wang H, Zha YF. The influences of vertebral level and age on perfusion parameters of thoracic-lumbar vertebral marrow in adults using T1-Weighted dynamic contrast enhancement MRI, ISMRM, 2013.

  45. Sui Y, Liu GZ, Wang H, Damen FC, Li YH, Zhou XJ. Comparison of Three Non-Gaussian Diffusion Models for Differentiation of Pediatric Brain Tumors, ISMRM, 2013.

  46. Zhou Y, Liu JY, Wang H, Sun N. Comparing of mono-exponential, bi-exponential and stretched exponential models with multi-b value Diffusion Weighed imaging in uterus malignancies pilot study, ISMRM, 2013.

  47. Lou HY, Zhang R, Zhang JF, Wang QD, Tong Y, Xu SL, Wang H. Preliminary experience with visualization of susceptibility signal patterns to differentiate intracranial hemangiopericytomas and meningiomas by T2* weighted angiography imaging, ISMRM, 2013.

  48. Zhu WZ, Xiong W, Wang H, Qin YY. Intravoxel distribution of water diffusion rates reveals proliferative activity in human astrocytoma, ISMRM, 2013.

  49. Ma C, Pan CS, Wang H, Chen SY, Lu JP. Diffusion-Weighted Magnetic Resonance Imaging of Healthy Pancreas: The Effect of Age on Apparent Diffusion Coefficient Values, ISMRM, 2013.

  50. Ma C, Li YJ, Wang H, Chen SY, Lu JP. High Resolution Diffusion Weighted Imaging of Pancreatic neoplasms using 2D ss-rFOV-DWEPI at 3 Tesla, ISMRM, 2013.

  51. Zhang Y, Wang H, Cao G, Mao Q, Ding B, Ling HW. Voxel-based analysis of cerebral perfusion changes in Alzheimer disease and mild cognitive impairment measured with a novel 3D arterial spin labeling technique, ISMRM, 2013.

  52. Zhang Y, Wang H, Cao G, Zhang L, Zhang GX. Investigation of functional connectivity changes in Alzheimer disease using degree centrality, ISMRM, 2013.

  53. Wang H, Sun YS, Zhang Y, Cao G. Diffusion behavior in rectal cancer: comparison of mono-exponential bi-exponential  and continuously distributed exponential models, ISMRM, 2012.

  54. Sui Y, Wang H, Liu GZ , Damen FW, Wanamaker C, Li YH, Zhou XJ. Differentiation of Low- and High-Grade Pediatric Brain Tumors Using High b-Value Diffusion Imaging with A Fractional Order Calculus Model, ISMRM, 2012.

  55. Chen J, Wang Y, Deng J, Mccarthy RJ, Wang GW, Ye YJ, Wang H, Du XK. Predict Metastatic and Benign Lymph Nodes in Patients with Gastric Carcinoma by Using Diffusion-Weighted Imaging, ISMRM, 2012.

  56. Chen HY, Chen YF, Wang H, Yang YB, Cao G, Yan X. A Preliminary Study Evaluating the Functional Diffusion Map for Early Detection of TACE Treatment Response in Patients with Liver Carcinoma, ISMRM, 2012.

  57. Mu KT, Zhang J, Wang H, Qi JP, Zhu WZ. The clinical application of 3T PROPELLER DUO MRI quantitative analysis of extraocular muscle in Grave’s ophthalmopathy, ISMRM, 2012.

  58. Zhu WZ, Wang H. The application of multiple b-value DWI with the stretched- exponential model in the preoperative grading of cerebral glioma, ISMRM, 2012.

  59. Feng Q, Zhu J, Lu Q, Wang H, Hua J, Xu JR. Respiratory-triggered High-b-value Diffusion-weighted Imaging for the Assessment of Inflammatory Activity in Crohn’s Disease: A Preliminary Study, ISMRM, 2012.

  60. Wang H, Zhang Y, Cao G. Evaluation of a Novel Continuously Distributed Diffusion Model in Normal Human Brain, ISMRM, 2011.

  61. Xia Z, Li Y, Wang H. The application of T2 Star Weighted Angiography (SWAN) in Hypoxic-ischemic encephalopathy, ISMRM, 2011.

  62. Yao XZ, Zeng MS, Wang H, Sun F, Rao SX, Ji Y. Normal pancreas and pancreatic cancer: comparison among different diffusion weighted MR imaging acquisitions at 3.0T, ISMRM, 2011.